Extracorporeal membrane oxygenation (ECMO) is a life-saving technique that is widely being used in centers throughout the\nworld. However, there is a paucity of literature surrounding the mechanisms affecting cerebral physiology while on ECMO.\nStudies have shown alterations in cerebral blood flow characteristics and subsequently autoregulation. Furthermore, the mechanical\naspects of the ECMO circuit itself may affect cerebral circulation. The nature of these physiological/pathophysiological\nchanges can lead to profound neurological complications. This review aims at describing the changes to normal cerebral\nautoregulation during ECMO, illustrating the various neuromonitoring tools available to assess markers of cerebral autoregulation,\nand finally discussing potential neurological complications that are associated with ECMO.
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